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Biological Safety Cabinets [Class I, II & III]

The Baker Company’s biological safety cabinets are designed to far exceed NSF-49 requirements. Through innovation, Baker hoods provide personnel, product and environmental protection while also saving energy and providing an ergonomic working environment. Baker hoods have earned a reputation for being the longest lasting with the lowest life cycle cost, and will offer many years of trouble-free operation.

A variety of biosafety cabinets that provide the highest level of performance

A biological safety cabinet, also known as a biosafety cabinet, is an important piece of safety equipment in any lab that will protect you, others, and your space from infectious droplets and aerosols. The Centers for Disease Control and Prevention (CDC) defines biological safety cabinets (BSCs) as “the primary means of containment developed for working safely with infectious microorganisms.”

The most common cabinets are Class II BSCs, which provide protection for you and those in your lab, samples and products, and the environment. Class I provides protection for you and the environment, but not your samples. Class III provides the most protection since the enclosure is gas-tight.

We offer a variety of Class II and III biosafety cabinets that provide the highest level of performance, user convenience and comfort, and energy efficiency. Some models can save you up to 70% annually in operating costs due to a large reduction in energy consumption and heat yields. Additionally, our models are equipped to handle a variety of biosafety levels  (BSLs). They also meet and exceed NSF 49.


The SterilGARD e3 is designed for many applications involving agents of low and moderate risk, including sterile product preparation and biological experimentation. BSL-1, BSL-2, BSL-3
The NCB is intended for lab procedures, including microbiological studies, cell culture, pharmaceutical procedures and toxicology. BSL-1, BSL-2, BSL-3
BioChemGARD e3 series is designed for labs that need containment and removal of vapors, mists and particulates. BSL-2 and BSL-3

Biological Safety Cabinet Considerations

There are many important factors to consider when purchasing a biological safety cabinet, including:

  • Sizes: Our biosafety cabinets come in a range of sizes designed to suit your lab space needs. Hood widths are 3’, 4’, 5’, and 6’.
  • Monitoring and alerts: All units have an audible alarm and a flashing LED to indicate when the sliding viewscreen is in an unsafe position. They also come with a mute switch, which allows the operator to mute the alarm tone for brief adjustments. Some have the capability of indicating a power loss at the panel and visual and audible alarms. A few biological safety cabinets feature an audible/visual airflow alarm and automatic shutoff system called the Airflow Monitor (AFM), which warns when the exhaust airflow decreases.
  • HEPA filtration: All BSCs come with a supply and exhaust filter. The Class II B1 is unique in that it has two supply filters. What differentiates the Class II BSC is the percentage of air that recirculates through the supply filter and what percentage of air goes through the exhaust filter. The Class III models feature full-coverage, ceiling-mounted supply HEPA filters to ensure an ISO Class 4 operating environment. Your sales specialist can help determine what BSC is right for your application.
  • Ergonomics: Many of our models feature exclusive National Science Foundation-approved cable ports, which allow a safe and ergonomic way of introducing cables and siphoning tubes into the cabinet without interfering with the containment. The Class III models offer an adaptive ergonomic design, including a 10° slanted viewscreen and stainless steel gloveports built directly into the viewscreen. The viewscreen, which is scratch resistant and protects against most decontamination agents, provides maximum safety and reduces eye strain.
  • Energy efficiency: Our models feature a ReadySAFE mode, which uses 50-75% less energy during off hours.
  • Durability and reliability: The Class II models include a StediFLOWTM VFD motor controller, which improves performance, extends the filter life and reduces operating costs and downtime by regulating airflow more efficiently. The Class III models are built to the highest leak-tightness specifications, and each IsoGARD model undergoes a Class III helium leak test prior to shipping.
  • Biological safety cabinet classes: Your choice of cabinet depends on what level of protection you need for laboratory workers, the space, and the samples. Class II BSCs protect you, people in your lab, samples and products and the environment. Class I provides protection for you and the environment, but not your samples. Class III provides the most protection since the enclosure is gas-tight. The Class III models include the same state-of-the-art features as the Class II cabinets, in addition to a primary physical barrier that offers protection between the lab investigator and the biological agent.

Trusted By

In 2019, we purchased two Baker STERILGARD biosafety cabinets (BSCs) through DAI. This model BSC offered numerous desired features at a very reasonable price. Our local sales representative through DAI was extremely helpful! He provided a wealth of information regarding the BSCs, as well as documentation we required to process the purchase. Dan was key in arranging for inside delivery directly to our labs through a company that had extensive experience with setup and delivery of Baker BSCs. The delivery and setup of these large pieces of equipment could not have gone more smoothly. Dan was also on-site for the delivery and provided a thorough tutorial on the use of the new BSCs at that time.
Edward Hines, Jr. VA Hospital
Can I install an independent temperature monitoring system?
All our lab freezers provide an access port for you to install your temperature probe into the freezer. To save money, a lot of customers use a low-cost residential freezer that does not have an access port for the temperature probe, which means they run the probe through the door gasket. The probe cord causes an air gap along the door gasket line. This allows warm room air to enter the freezer, which accelerates the frost buildup.  
Do you have backup options?
Yes, the most common is a liquid CO2 backup, but we also have a LN2 backup option. For most -80°C applications, a liquid CO2 with suffice. For our cryogenic -150°C freezer, you should opt for the LN2 backup.
Do you have light sensitive options?
Yes, we have solid door models and even black-out panel options for glass door models.
Do you have models that meet the new energy standards?
We have options from small table top, undercounter, all the way to 72 cuft, 3 door units.
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